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Title: The imminent role of protein engineering in synthetic biology
Authors: Foo, Jee Loon
Ching, Chi Bun
Chang, Matthew Wook
Leong, Susanna Su Jan
Issue Date: 2012
Source: Foo, J. L., Ching, C. B., Chang, M. W.,& Leong, S. S. J. (2012). The imminent role of protein engineering in synthetic biology. Biotechnology Advances, 30(3), 541-549.
Series/Report no.: Biotechnology advances
Abstract: Protein engineering has for decades been a powerful tool in biotechnology for generating vast numbers of useful enzymes for industrial applications. Today, protein engineering has a crucial role in advancing the emerging field of synthetic biology, where metabolic engineering efforts alone are insufficient to maximize the full potential of synthetic biology. This article reviews the advancements in protein engineering techniques for improving biocatalytic properties to optimize engineered pathways in host systems, which are instrumental to achieve high titer production of target molecules. We also discuss the specific means by which protein engineering has improved metabolic engineering efforts and provide our assessment on its potential to continue to advance biology engineering as a whole.
ISSN: 0734-9750
DOI: 10.1016/j.biotechadv.2011.09.008
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SCBE Journal Articles

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