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Title: In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
Authors: Wang, Chao
Teng, Xue
Cheng, Kai
Cheng, Zhen
Huang, Ling
Liu, Zhuang
Liu, Xiaogang
Xing, Bengang
Yang, Yanmei
Shao, Qing
Deng, Renren
Issue Date: 2012
Source: Yang, Y., Shao, Q., Deng, R., Wang, C., Teng, X., Cheng, K., et al. (2012). In Vitro and In Vivo Uncaging and Bioluminescence Imaging by Using Photocaged Upconversion Nanoparticles. Angewandte Chemie International Edition, 51(13), 3125-3129.
Series/Report no.: Angewandte chemie international edition
Abstract: Trading up: A bioimaging system that is based on caged D-luciferin/upconversion nanoparticle conjugate has been developed. The nanoparticles upconvert near-infrared light into UV light, which triggers the photorelease of D-luciferin (see scheme) and leads to enhanced fluorescence and bioluminescence signals in vitro and in vivo. The use of near-infrared light enables deep penetration into tissue in vivo with minimum cellular damage.
ISSN: 1433-7851
DOI: 10.1002/anie.201107919
Rights: © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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