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Title: A Pt(II)-dip complex stabilizes parallel c-myc G-quadruplex
Authors: Wang, Jintao
Lu, Kaihui
Xuan, Shuguang
Toh, Zaozhen
Zhang, Dawei
Shao, Fangwei
Keywords: DRNTU::Science::Mathematics
Issue Date: 2013
Source: Wang, J., Lu K., Xuan, S., Toh, Z., Zhang, D., & Shao F. (2013). A Pt(II)-Dip complex stabilizes parallel c-myc G-quadruplex. Chemical Communications, 49(42), 4758-4760.
Series/Report no.: Chemical communications
Abstract: A new G-quadruplex (GQ) stabilizer, [Pt(Dip)2](PF6)2 (Dip: 4,7-diphenyl-1,10-phenanthroline), is prepared by the microwave irradiation method. The complex can highly stabilize G-quadruplex, but has negligible interactions with duplex DNA. Aromatic anchors on the polypyridyl ligands bestow the stabilizer with a high binding preference towards parallel GQ.
DOI: 10.1039/c3cc40868j
Rights: © 2013 The Royal Society of Chemistry This is the author created version of a work that has been peer reviewed and accepted for publication by Chemical Communications, The Royal Society of Chemistry. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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