Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/99731
Full metadata record
DC FieldValueLanguage
dc.contributor.authorRice, Scott A.en
dc.contributor.authorKardak, Bharat G.en
dc.contributor.authorKelso, Michael J.en
dc.contributor.authorYepuri, Nageshwar Raoen
dc.contributor.authorBarraud, Nicolasen
dc.contributor.authorMohammadi, Nasim Shahen
dc.contributor.authorKjelleberg, Staffanen
dc.date.accessioned2013-11-08T07:50:29Zen
dc.date.accessioned2019-12-06T20:10:49Z-
dc.date.available2013-11-08T07:50:29Zen
dc.date.available2019-12-06T20:10:49Z-
dc.date.copyright2013en
dc.date.issued2013en
dc.identifier.citationYepuri, N. R., Barraud, N., Mohammadi, N. S., Kardak, B. G., Kjelleberg, S., Rice, S. A., et al. (2013). Synthesis of cephalosporin-3′-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase. Chemical communications, 49(42), 4791-4793.en
dc.identifier.urihttps://hdl.handle.net/10356/99731-
dc.description.abstractUse of biofilm dispersing NO-donor compounds in combination with antibiotics has emerged as a promising new strategy for treating drug-resistant bacterial biofilm infections. This paper details the synthesis and preliminary evaluation of six cephalosporin-3′-diazeniumdiolates as biofilm-targeted NO-donor prodrugs. Each of the compounds is shown to selectively release NO following reaction with the bacteria-specific enzyme β-lactamase and to trigger dispersion of Pseudomonas aeruginosa biofilms in vitro.en
dc.language.isoenen
dc.relation.ispartofseriesChemical communicationsen
dc.subjectBiofilmsen
dc.titleSynthesis of cephalosporin-3′-diazeniumdiolates : biofilm dispersing NO-donor prodrugs activated by β-lactamaseen
dc.typeJournal Articleen
dc.identifier.doi10.1039/c3cc40869hen
item.grantfulltextnone-
item.fulltextNo Fulltext-
Appears in Collections:SCELSE Journal Articles

SCOPUSTM   
Citations 5

32
checked on Aug 31, 2020

WEB OF SCIENCETM
Citations 50

29
checked on Sep 16, 2020

Page view(s) 50

444
checked on Sep 23, 2020

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.