Now showing items 13881-13900 of 20715

    • p-doping-free InGaN/GaN light-emitting diode driven by three-dimensional hole gas 

      Zhang, Zi-Hui; Tan, Swee Tiam; Kyaw, Zabu; Liu, Wei; Ji, Yun; Ju, Zhengang; Zhang, Xueliang; Sun, Xiao Wei; Demir, Hilmi Volkan (2013)
      Here, GaN/AlxGa1-xN heterostructures with a graded AlN composition, completely lacking external p-doping, are designed and grown using metal-organic-chemical-vapour deposition (MOCVD) system to realize three-dimensional ...
    • A P-loop mutation in Gα subunits prevents transition to the active state : implications for G-protein signaling in fungal pathogenesis 

      Bosch, Dustin E.; Willard, Francis S.; Ramanujam, Ravikrishna.; Kimple, Adam J.; Willard, Melinda D.; Naqvi, Naweed Issak.; Siderovski, David P. (2012)
      Heterotrimeric G-proteins are molecular switches integral to a panoply of different physiological responses that many organisms make to environmental cues. The switch from inactive to active Gαβγ heterotrimer relies on ...
    • p-type Bi0.4Sb1.6Te3 nanocomposites with enhanced figure of merit 

      Fan, Shufen; Zhao, Junnan; Guo, Jun; Yan, Qingyu; Ma, Jan; Hng, Huey Hoon (2010)
      We report enhanced figure of merit, ZT, in p-type Bi0.4Sb1.6Te3 nanocomposites fabricated by a rapid and high throughput method of mixing nanostructured Bi0.4Sb1.6Te3 particles obtained through melt spinning with micronsized ...
    • P1dB optimization methodology for 130 nm SiGe BiCMOS 60GHz power amplifier 

      Wu, Wenguang; Gu, Jiangmin; Lim, Wei Meng; Yao, Feijie; Sui, Wenquan; Siek, Liter (2015)
      A four-stage cascade power amplifier (PA) in 60 GHz industrial scientific medical (ISM) band is realized in 130 nm SiGe BiCMOS process. The PA employs single-ended topology with transistors in common-emitter. The design ...
    • p27 is regulated independently of Skp2 in the absence of Cdk2 

      Kotoshiba, Shuhei; Gopinathan, Lakshmi; Pfeiffenberger, Elisabeth; Rahim, Anisa; Vardy, Leah Karen Anne; Nakayama, Keiko; Nakayama, Keiichi I.; Kaldis, Philipp (2014)
      Cyclin-dependent kinase 2 (Cdk2) is dispensable for mitotic cell cycle progression and Cdk2 knockout mice are viable due to the compensatory functions of other Cdks. In order to assess the role of Cdk2 under limiting ...
    • P53 gene targeting by homologous recombination in fish ES cells 

      Yan, Yan; Hong, Ni; Chen, Tiansheng; Li, Mingyou; Wang, Tiansu; Guan, Guijun; Qiao, Yongkang; Chen, Songlin; Schartl, Manfred; Li, Chang Ming; Hong, Yunhan (2013)
      Gene targeting (GT) provides a powerful tool for the generation of precise genetic alterations in embryonic stem (ES) cells to elucidate gene function and create animal models for human diseases. This technology has, ...
    • P53 maintains genomic stability by preventing interference between transcription and replication 

      Yeo, Constance Qiao Xin; Alexander, Irina; Lin, Zhaoru; Lim, Shuhui; Aning, Obed Akwasi; Kumar, Ramesh; Sangthongpitag, Kanda; Pendharkar, Vishal; Ho, Vincent H.B.; Cheok, Chit Fang (2016)
      p53 tumor suppressor maintains genomic stability, typically acting through cell-cycle arrest, senescence, and apoptosis. We discovered a function of p53 in preventing conflicts between transcription and replication, ...
    • p53-independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6 

      Phalke, Sameer; Mzoughi, Slim; Bezzi, Marco; Jennifer, Nancy; Mok, Wei Chuen; Low, Diana H. P.; Thike, Aye Aye; Kuznetsov, Vladimir A.; Tan, Puay Hoon; Voorhoeve, P. Mathijs; Guccione, Ernesto (2012)
      p21 is a potent cyclin-dependent kinase inhibitor that plays a role in promoting G1 cell cycle arrest and cellular senescence. Consistent with this role, p21 is a downstream target of several tumour suppressors and oncogenes, ...
    • p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice 

      Burla, Romina; La Torre, Mattia; Zanetti, Giorgia; Bastianelli, Alex; Merigliano, Chiara; Del Giudice, Simona; Vercelli, Alessandro; Di Cunto, Ferdinando; Boido, Marina; Vernì, Fiammetta; Saggio, Isabella (2018)
      Epilepsy is a complex clinical condition characterized by repeated spontaneous seizures. Seizures have been linked to multiple drivers including DNA damage accumulation. Investigation of epilepsy physiopathology in humans ...
    • The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans 

      Coffill, Cynthia R.; Lee, Alison P.; Siau, Jia Wei; Chee, Sharon M.; Joseph, Thomas L.; Tan, Yaw Sing; Madhumalar, Arumugam; Tay, Boon-Hui; Brenner, Sydney; Verma, Chandra Shekhar; Ghadessy, Farid J.; Venkatesh, Byrappa; Lane, David P. (2016)
      The extant jawless vertebrates, represented by lampreys and hagfish, are the oldest group of vertebrates and provide an interesting genomic evolutionary pivot point between invertebrates and jawed vertebrates. Through ...
    • Packed bed regenerators using cascaded phase change materials : overcharging and possible solutions 

      Khor, Jun Onn; Li, Yongliang; Romagnoli, Alessandro (2018)
      In this paper, packed bed regenerators using different phase change materials cascaded in series for cold energy storage are investigated with specific focus on charging behaviour. Indeed, when one phase change material ...
    • PADLs : supporting digital scholarship in digital libraries 

      Goh, Dion Hoe-Lian (2001)
      This paper introduces digital scholarship, a process in which individuals perform all scholarly work electronically, working entirely with digital media. A proposal is made for patronaugmented ...
    • A PAE of 17.5% Ka-band balanced frequency doubler with conversion gain of 20 dB 

      Li, Jiankang; Lu, Zhong; Xiong, Yong-Zhong; Hou, Debin; Wang, Ren; Goh, Wang Ling; Wu, Wen (2012)
      A frequency doubler from 27 to 41 GHz fabricated in 0.13-μm SiGe BiCMOS technology with a maximum output power of 8 dBm and a power added efficiency (PAE) of 17.5% at dc power consumption of 35 mW is presented. It consists ...
    • Paediatric trauma systems and their impact on the health outcomes of severely injured children: protocol for a mixed methods cohort study 

      Curtis, Kate; McCarthy, Amy; Mitchell, Rebecca; Black, Deborah; Foster, Kim; Jan, Stephen; Burns, Brian; Tall, Gary; Rigby, Oran; Gruen, Russell; Kennedy, Belinda; Holland, Andrew J. A. (2016)
      Background: Injury is a leading cause of death and disability for children. Regionalised trauma systems have improved outcomes for severely injured adults, however the impact of adult orientated trauma systems on the ...
    • Pair-hopping characteristic of lithium diffusive motion in Li-doped β-phase manganese phthalocyanine 

      Du, Xiaosong; Li, Qunxiang; Chen, Ying; Su, Haibin; Yang, Jinlong (2007)
      We report a first-principles molecular dynamics study on Li-doped beta-phase manganese phthalocyanine (MnPc). Four electronegative sites next to pyrrole-bridging nitrogen atoms in single MnPc were characterized by analyzing ...
    • Pairing correlations in the two-layer attractive Hubbard model 

      Zujev, Aleksander; Scalettar, Richard T.; Batrouni, George G.; Sengupta, Pinaki (2014)
      Studies of systems with two fermionic bands (or equivalently, layers) with repulsive interaction strength U have a long history, with the periodic Anderson model (PAM) being one of the most frequently considered Hamiltonians. ...
    • Pairs of partitions without repeated odd parts 

      Chan, Song Heng; Mao, Renrong (2012)
      We prove two identities related to overpartition pairs. One of them gives a generalization of an identity due to Lovejoy, which was used in a joint work by Bringmann and Lovejoy to derive congruences for overpartition ...
    • Pairs trading : a copula approach 

      Liew, Rong Qi; Wu, Yuan (2013)
      Pairs trading is a technique that is widely practiced in the financial industry. Its relevance has been constantly tested with updated samples, and its profitability is acknowledged among practitioners and academics. Yet ...
    • Pairwise alignment of DNA sequence using hypercomplex number representation 

      Shu, Jian Jun; Ouw, Li Shan (2004)
      A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the ...
    • Pairwise alignment of the DNA sequence using hypercomplex number representation 

      Shu, Jian Jun; Ouw, Li Shan (2004)
      A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the ...