Now showing items 1-2 of 2

    • MiR‐135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF‐β/BMP signaling 

      Bhinge, Akshay; Poschmann, Jeremie; Namboori, Seema C.; Tian, Xianfeng; Loh, Sharon Jia Hui; Traczyk, Anna; Prabhakar, Shyam; Stanton, Lawrence W. (2014)
      Several transcription factors (TFs) have been implicated in neuroectoderm (NE) development, and recently, the TF PAX6 was shown to be critical for human NE specification. However, microRNA networks regulating human NE ...
    • The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis 

      Leow, Shi Chi; Poschmann, Jeremie; Too, Peh Gek; Yin, Juan; Joseph, Roy; McFarlane, Craig; Dogra, Shaillay; Shabbir, Asim; Ingham, Philip William; Prabhakar, Shyam; Leow, Melvin K. S.; Lee, Yung Seng; Ng, Kai Lyn; Chong, Yap Seng; Gluckman, Peter D.; Stünkel, Walter (2016)
      An association between impaired fetal growth and the postnatal development of obesity has been established. Here, by comparing adipocytes differentiated from mesenchymal stem cells (MSCs) taken from the umbilical cord and ...