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    • HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis 

      Yan, TingDong; Ooi, Wen Fong; Qamra, Aditi; Cheung, Alice; Ma, DongLiang; Sundaram, Gopinath Meenakshi; Xu, Chang; Xing, Manjie; Poon, LaiFong; Wang, Jing; Loh, Yan Ping; Ho, Jess Hui Jie; Ng, Joscelyn Jun Quan; Muhammad Khairul Ramlee; Aswad, Luay; Rozen, Steve G.; Ghosh, Sujoy; Bard, Frederic A.; Sampath, Prabha; Tergaonkar, Vinay; Davies, James O.J.; Hughes, Jim R.; Goh, Eyleen; Bi, Xuezhi; Fullwood, Melissa Jane; Tan, Patrick; Li, Shang (2017)
      The repression of telomerase activity during cellular differentiation promotes replicative aging and functions as a physiological barrier for tumorigenesis in long-lived mammals, including humans. However, the underlying ...