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The natively disordered loop of Bcl-2 undergoes phosphorylation-dependent conformational change and interacts with Pin1
Bcl-2 plays a central role in the regulation of apoptosis. Structural studies of Bcl-2 revealed the presence of a flexible and natively disordered loop that bridges the Bcl-2 homology motifs, BH3 and BH4. This loop is ...