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Stimulation of transcript elongation requires both the zinc finger and RNA polymerase II binding domains of human TFIIS
The eukaryotic transcriptional factor TFIIS enhances transcript elongation by RNA polymerase II. Here we describe two functional domains in the 280 amino acid human TFIIS protein: residues ...
Cloning, expression and characterization of the human transcription elongation factor, TFIIS
The cDNA for the human elongation factor, TFIIS, has been cloned and expressed in E. coil with the T7 expression system. This 280-amino acid TFIIS protein is shorter by 21 residues than that of the mouse. The missing 21 ...