Now showing items 1-2 of 2
Stapled peptides as a new technology to investigate protein–protein interactions in human platelets
Platelets are blood cells with numerous crucial pathophysiological roles in hemostasis, cardiovascular thrombotic events and cancer metastasis. Platelet activation requires the engagement of intracellular signalling pathways ...
Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
The discovery of new Protein–Protein Interaction (PPI) modulators is currently limited by the difficulties associated with the design and synthesis of selective small molecule inhibitors. Peptides are a potential solution ...