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An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids
An on-nanoparticle rolling-circle amplification (nanoRCA) strategy allows the visual detection of 30 molecules of carcinoembryonic antigen with at least 1010-fold selectivity over a range of noncognate proteins. The nanoRCA ...
Aptamer-based multicolor fluorescent gold nanoprobes for multiplex detection in homogeneous solution
The design of a novel multicolor fluorescent gold nanoprobe for homogeneous detection of small-molecule targets is reported, which combines the specific binding abilities of aptamers with the ultrahigh quenching ability ...