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Empirical modeling of the fine particle fraction for carrier-based pulmonary delivery formulations
In vitro study of the deposition of drug particles is commonly used during development of formulations for pulmonary delivery. The assay is demanding, complex, and depends on: properties of the drug and carrier particles, ...
Heuristic modeling of macromolecule release from PLGA microspheres
Dissolution of protein macromolecules from poly(lactic-co-glycolic acid) (PLGA) particles is a complex process and still not fully understood. As such, there are difficulties in obtaining a predictive model that could be ...