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Sugar-based synthesis of Tamiflu and its inhibitory effects on cell secretion
Tamiflu is currently the most effective drug for the treatment of influenza, but the insufficient supply and side-effects of this drug demand urgent solutions. We present a practical synthesis of Tamiflu by using novel ...
Control of adipogenesis by the autocrine interplays between angiotensin 1–7/mas receptor and angiotensin II/AT1 receptor signaling pathways
Angiotensin II (AngII), a peptide hormone released by adipocytes, can be catabolized by adipose angiotensin-converting enzyme 2 (ACE2) to form Ang(1-7). Co-expression of AngII receptors (AT1 and AT2) and Ang(1-7) receptors ...