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Surface immobilized cholera toxin B subunit (CTB) facilitates vesicle docking, trafficking and exocytosis
The subunit B of cholera toxin (CTB), which specifically binds with ganglioside GM1 enriched in membrane lipid rafts, is known to interfere with multiple cell functions. However, the specific, stable and spatially ...
DNA-templated silver nanoclusters for multiplexed fluorescent DNA detection
Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and ...
The molecular basis of distinct aggregation pathways of islet amyloid polypeptide
Abnormal aggregation of islet amyloid polypeptide (IAPP) into amyloid fibrils is a hallmark of type 2 diabetes. In this study, we investigated the initial oligomerization and subsequent addition of monomers to growing ...