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Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Warren, Helen R; Evangelou, Evangelos; Cabrera, Claudia P; Gao, He; Ren, Meixia; Mifsud, Borbala; Ntalla, Ioanna; Surendran, Praveen; Liu, Chunyu; Cook, James P; Kraja, Aldi T; Drenos, Fotios; Loh, Marie; Verweij, Niek; Marten, Jonathan; Karaman, Ibrahim; Lepe, Marcelo P Segura; O'Reilly, Paul F; Knight, Joanne; Snieder, Harold; Kato, Norihiro; He, Jiang; Tai, E Shyong; Said, M Abdullah; Porteous, David; Alver, Maris; Poulter, Neil; Farrall, Martin; Gansevoort, Ron T; Padmanabhan, Sandosh; Mägi, Reedik; Stanton, Alice; Connell, John; Bakker, Stephan J L; Metspalu, Andres; Shields, Denis C; Thom, Simon; Brown, Morris; Sever, Peter; Esko, Tõnu; Hayward, Caroline; van der Harst, Pim; Saleheen, Danish; Chowdhury, Rajiv; Chambers, John Campbell; Chasman, Daniel I; Chakravarti, Aravinda; Newton-Cheh, Christopher; Lindgren, Cecilia M; Levy, Daniel; Kooner, Jaspal S; Keavney, Bernard; Tomaszewski, Maciej; Samani, Nilesh J; Howson, Joanna M M; Tobin, Martin D; Munroe, Patricia B; Ehret, Georg B; Wain, Louise V; Wain, Louise V; Vaez, Ahmad; Jansen, Rick; Joehanes, Roby; van der Most, Peter J; Erzurumluoglu, A Mesut; O'Reilly, Paul; Cabrera, Claudia P; Warren, Helen R; Rose, Lynda M; Verwoert, Germaine C; Hottenga, Jouke-Jan; Strawbridge, Rona J; Esko, Tonu; Arking, Dan E; Hwang, Shih-Jen; Guo, Xiuqing; Kutalik, Zoltan; Trompet, Stella; Shrine, Nick; Teumer, Alexander; Ried, Janina S; Bis, Joshua C; Smith, Albert V; Amin, Najaf; Nolte, Ilja M; Lyytikäinen, Leo-Pekka; Mahajan, Anubha; Wareham, Nicholas J; Hofer, Edith; Joshi, Peter K; Kristiansson, Kati; Traglia, Michela; Havulinna, Aki S; Goel, Anuj; Nalls, Mike A; Sõber, Siim; Vuckovic, Dragana; Luan, Jian'an; M, Fabiola Del Greco; Ayers, Kristin L; Marrugat, Jaume; Ruggiero, Daniela; Lopez, Lorna M; Niiranen, Teemu; Enroth, Stefan; Jackson, Anne U; Nelson, Christopher P; Huffman, Jennifer E; Zhang, Weihua; Marten, Jonathan; Gandin, Ilaria; Harris, Sarah E; Zemonik, Tatijana; Lu, Yingchang; Evangelou, Evangelos; Shah, Nabi; de Borst, Martin H; Mangino, Massimo; Prins, Bram P; Campbell, Archie; Li-Gao, Ruifang; Chauhan, Ganesh; Oldmeadow, Christopher; Abecasis, Gonçalo; Abedi, Maryam; Barbieri, Caterina M; Barnes, Michael R; Batini, Chiara; Blake, Tineka; Boehnke, Michael; Bottinger, Erwin P; Braund, Peter S; Brown, Morris; Brumat, Marco; Campbell, Harry; Cocca, Massimiliano; Collins, Francis; Connell, John; Cordell, Heather J; Damman, Jeffrey J; Davies, Gail; de Geus, Eco J; de Mutsert, Renée; Deelen, Joris; Demirkale, Yusuf; Doney, Alex S F; Dörr, Marcus; Farrall, Martin; Ferreira, Teresa; Frånberg, Mattias; Gao, He; Giedraitis, Vilmantas; Gieger, Christian; Giulianini, Franco; Gow, Alan J; Hamsten, Anders; Harris, Tamara B; Hofman, Albert; Holliday, Elizabeth G; Jarvelin, Marjo-Riitta; Johansson, Åsa; Johnson, Andrew D; Jousilahti, Pekka; Jula, Antti; Kähönen, Mika; Kathiresan, Sekar; Khaw, Kay-Tee; Kolcic, Ivana; Koskinen, Seppo; Langenberg, Claudia; Larson, Marty; Launer, Lenore J; Lehne, Benjamin; Liewald, David C M; Lin, Li; Lind, Lars; Mach, François; Mamasoula, Chrysovalanto; Menni, Cristina; Mifsud, Borbala; Milaneschi, Yuri; Morgan, Anna; Morris, Andrew D; Morrison, Alanna C; Munson, Peter J; Nandakumar, Priyanka; Nguyen, Quang Tri; Nutile, Teresa; Oldehinkel, Albertine J; Oostra, Ben A; Org, Elin; Padmanabhan, Sandosh; Palotie, Aarno; Paré, Guillaume; Pattie, Alison; Penninx, Brenda W J H; Poulter, Neil; Pramstaller, Peter P; Raitakari, Olli T; Ren, Meixia; Rice, Kenneth; Ridker, Paul M; Riese, Harriëtte; Ripatti, Samuli; Robino, Antonietta; Rotter, Jerome I; Rudan, Igor; Saba, Yasaman; Pierre, Aude Saint; Sala, Cinzia F; Sarin, Antti-Pekka; Schmidt, Reinhold; Scott, Rodney; Seelen, Marc A; Shields, Denis C; Siscovick, David; Sorice, Rossella; Stanton, Alice; Stott, David J; Sundström, Johan; Swertz, Morris; Taylor, Kent D; Thom, Simon; Tzoulaki, Ioanna; Tzourio, Christophe; Uitterlinden, André G; Völker, Uwe; Vollenweider, Peter; Wild, Sarah; Willemsen, Gonneke; Wright, Alan F; Yao, Jie; Thériault, Sébastien; Conen, David; John, Attia; Sever, Peter; Debette, Stéphanie; Mook-Kanamori, Dennis O; Zeggini, Eleftheria; Spector, Tim D; van der Harst, Pim; Palmer, Colin N A; Vergnaud, Anne-Claire; Loos, Ruth J F; Polasek, Ozren; Starr, John M; Girotto, Giorgia; Hayward, Caroline; Kooner, Jaspal S; Lindgren, Cecila M; Vitart, Veronique; Samani, Nilesh J; Tuomilehto, Jaakko; Gyllensten, Ulf; Knekt, Paul; Deary, Ian J; Ciullo, Marina; Elosua, Roberto; Keavney, Bernard D; Hicks, Andrew A; Scott, Robert A; Gasparini, Paolo; Laan, Maris; Liu, YongMei; Watkins, Hugh; Hartman, Catharina A; Salomaa, Veikko; Toniolo, Daniela; Perola, Markus; Wilson, James F; Schmidt, Helena; Zhao, Jing Hua; Lehtimäki, Terho; van Duijn, Cornelia M; Gudnason, Vilmundur; Psaty, Bruce M; Peters, Annette; Rettig, Rainer; James, Alan; Jukema, J Wouter; Strachan, David P; Palmas, Walter; Metspalu, Andres; Ingelsson, Erik; Boomsma, Dorret I; Franco, Oscar H; Bochud, Murielle; Newton-Cheh, Christopher; Munroe, Patricia B; Elliott, Paul; Chasman, Daniel I; Chakravarti, Aravinda; Knight, Joanne; Morris, Andrew P; Levy, Daniel; Tobin, Martin D; Snieder, Harold; Caulfield, Mark J; Ehret, Georg B; Barnes, Michael R; Tzoulaki, Ioanna; Caulfield, Mark J; Elliott, Paul (2017)
Elevated blood pressure is the leading heritable risk factor for cardiovascular disease worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) among UK Biobank participants of ...
