Now showing items 1-6 of 6
High-throughput polymerase chain reaction in parallel circular loops using magnetic actuation
We report here a novel multichannel closed-loop magnetically actuated microchip for high-throughput polymerase chain reaction (PCR). This is achieved by designing a series of concentric circular channels on one microchip ...
Faster and improved microchip electrophoresis using a capillary bundle
Joule heating generated in capillary electrophoresis (CE) microchips is known to affect temperature gradient, electrophoretic mobility, diffusion of analytes, and ultimately the efficiency and reproducibility of the ...
Low-pressure, high-temperature thermal bonding of polymeric microfluidic devices and their applications for electrophoretic separation
A new method for thermally bonding poly(methyl methacrylate) (PMMA) substrates has been demonstrated. PMMA substrates are first engraved by CO2-laser micromachining to form microchannels. Both channel width and depth can ...
Rapid amplification of genetically modified organisms using a circular ferrofluid-driven PCR microchip
The use of genetically modified organisms (GMOs) as food and in food products is becoming more and more widespread. Polymerase chain reaction (PCR) technology is extensively used for the detection of GMOs in food products ...
Enhanced electrophoretic DNA separation in photonic crystal fiber
Joule heating generated by the electrical current in capillary electrophoresis leads to a temperature gradient along the separation channel and consequently affects the separation quality. We describe a method of reducing ...
A circular ferrofluid driven microchip for rapid polymerase chain reaction
In the past few years, much attention has been paid to the development of miniaturized polymerase chain reaction (PCR) devices. After a continuous flow (CF) PCR chip was introduced, several CFPCR systems employing various ...