Now showing items 1-6 of 6
α-palladation of Imines as entry to dehydrogenative heck reaction: Aerobic oxidative cyclization of N-Allylimines to Pyrroles
We report here a palladium(II)-catalyzed oxidative cyclization reaction of N-allylimines derived from methyl ketones, typically acetophenones, affording pyrrole derivatives at room temperature under oxygen atmosphere. The ...
Versatile synthesis of benzothiophenes and benzoselenophenes by rapid assembly of arylzinc reagents, alkynes, and elemental chalcogens
Rapidly aSSembled: The combination of cobalt-catalyzed migratory arylzincation and copper-mediated/catalyzed chalcogenative cyclization allows the construction of benzothiophenes and benzoselenophenes from arylzinc reagents, ...
Aldimine-directed branched-selective hydroarylation of styrenes
Branching out: A simple and inexpensive cobalt/triarylphosphine catalyst promotes aldimine-directed hydroarylation of styrene with high branched regioselectivity to afford 1,1-diarylethane derivatives in good yields under ...
Cobalt-catalyzed branched-selective addition of aromatic ketimines to styrenes under room-temperature conditions
An improved cobalt-based catalytic system has been developed for the branched-selective addition of aromatic ketimines to styrenes. With an appropriate combination of triarylphosphine and the Grignard reagent, the reaction ...
Cobalt-catalyzed ortho alkylation of aromatic imines with primary and secondary alkyl halides
We report here cobalt–N-heterocyclic carbene catalytic systems for the ortho alkylation of aromatic imines with alkyl chlorides and bromides, which allows the introduction of a variety of primary and secondary alkyl groups ...
Cobalt-catalyzed ortho-alkenylation of aromatic aldimines via chelation-assisted C–H bond activation
An ortho-alkenylation reaction of an aromatic aldimine with an internal alkyne is efficiently promoted by a cobalt catalyst generated from CoBr2, triarylphosphine, and iPrMgBr. The reaction takes place under mild ...