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Solution structure of the DNA-binding domain of a human papillomavirus E2 protein : evidence for flexible DNA-binding regions
The three-dimensional structure of the DNA-binding domain of the E2 protein from human papillomavirus-31 was determined by using multidimensional heteronuclear nuclear magnetic resonance (NMR) spectroscopy. A total of 1429 ...
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
THE Bcl-2 family of proteins regulate programmed cell death by an unknown mechanism1. Here we describe the crystal and solution structures of a Bcl-2 family member, Bcl-xL (ref. 2). The structures consist of two central, ...