Now showing items 1-4 of 4
Sugar-based synthesis of Tamiflu and its inhibitory effects on cell secretion
Tamiflu is currently the most effective drug for the treatment of influenza, but the insufficient supply and side-effects of this drug demand urgent solutions. We present a practical synthesis of Tamiflu by using novel ...
Surface immobilized cholera toxin B subunit (CTB) facilitates vesicle docking, trafficking and exocytosis
The subunit B of cholera toxin (CTB), which specifically binds with ganglioside GM1 enriched in membrane lipid rafts, is known to interfere with multiple cell functions. However, the specific, stable and spatially ...
The crosstalks between adipokines and catecholamines
Adipocytes, which secrete a spectrum of adipokines, play an integral role in metabolism via communications with other endocrine cells. In the present work, we have studied the interplays between adipokines and catecholamines, ...
Vesicular storage, vesicle trafficking, and secretion of leptin and resistin : the similarities, differences and interplays
Adipose tissue is a highly active endocrine organ secreting a variety of signaling molecules called adipokines. Leptin and resistin are two adipokines critically involved in metabolic homeostasis. Nevertheless, the secretory ...