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Molecular basis of Bcl-XL-p53 interaction : insights from molecular dynamics simulations
Bcl-XL, an antiapoptotic Bcl-2 family protein, plays a central role in the regulation of the apoptotic pathway. Heterodimerization of the antiapoptotic Bcl-2 family proteins with the proapoptotic family members such as ...
Targeting FK506 binding proteins to fight malarial and bacterial infections : current advances and future perspectives
There is an urgent need for the design and development of new and selective drugs for the treatment of malaria and bacterial infections as these pathogens are developing resistance to presently available therapies. Malaria ...