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Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
Eye diseases and injuries impose a significant clinical problem worldwide. Safe and effective ocular drug delivery is, however, challenging due to the presence of ocular barriers. Here we report a strategy using an eye ...
Semiconducting polymer nanobiocatalysts for photoactivation of intracellular redox reactions
An organic semiconducting polymer nanobiocatalyst (SPNB) composed of a semiconducting polymer core conjugated with microsomal cytochrome P450 (CYP) has been developed for photoactivation of intracellular redox. The core ...
Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics
Phototherapies including photothermal therapy (PTT) and photodynamic therapy (PDT) have gained considerable attention due to their high tumor ablation efficiency, excellent spatial resolution and minimal side effects on ...