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PKC epsilon facilitates recovery of exocytosis after an exhausting stimulation
It has been well documented that protein kinase Cs (PKCs) play multifaceted roles in regulating exocytosis of neurotransmitters and hormones. But the isoform-specific PKC effects are still poorly elucidated mainly because ...
Roles of cholesterol in vesicle fusion and motion
Although it is well established that exocytosis of neurotransmitters and hormones is highly regulated by numerous secretory proteins, such as SNARE proteins, there is an increasing appreciation of the importance of the ...
Involvement of PKC-alpha in PMA-induced facilitation of exocytosis and vesicle fusion in PC12 cells
Phorbol-12-myristate-13-acetate, a stable analog of the important signaling membrane lipid diacylglycerol (DAG), is known to potentiate exocytosis and modulate vesicle fusion kinetics in neurons and endocrine cells. The ...
Interfacing glycosylated carbon-nanotube-network devices with living cells to detect dynamic secretion of biomolecules
A sense of cell-being: Single-walled carbon nanotubes (SWNTs) are functionalized with bioactive monosaccharides to enable their use as biosensors. The glycosylated nanotube network is biocompatible and can interface with ...