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Validation of serum progesterone <35nmol/L as a predictor of miscarriage among women with threatened miscarriage
Background: Our recent paper, based on a pilot cohort of 119 women, showed that serum progesterone <35 nmol/L was prognostic of spontaneous miscarriage by 16 weeks in women with threatened miscarriage in early pregnancy. ...
Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress
Histological inspection of visually normal tissue adjacent to neoplastic lesions often reveals multiple foci of cellular abnormalities. This suggests the presence of a regional carcinogenic signal that spreads oncogenic ...
Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile
Threatened miscarriage is the most common gynecological emergency, occurring in about 20% of pregnant women. Approximately one in four of these patients go on to have spontaneous miscarriage and the etiology of miscarriage ...