Now showing items 671-672 of 672
The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domain
Retinoic acid-inducible gene I (RIG-I) is a pattern recognition receptor expressed in metazoan cells that is responsible for eliciting the production of type I interferons and pro-inflammatory cytokines upon detection of ...
The emerging role of Nrf2 in dermatotoxicology
The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects ...