Now showing items 61-63 of 63
A high-capacity scintillation proximity assay for the discovery and evaluation of ZAP-70 tandem SH2 domain antagonists
A scintillation proximity assay (SPA) is described, which quantitates the ability of compounds to inhibit the binding interaction of a select phosphopeptide with the tandem SH2 domains of the ZAP-70 protein tyrosine kinase. ...
Temperature dependence of excitonic energy in isolated Se chains formed in the channels of AlPO4-5 crystals
Optical absorption spectra of Se chains formed in channels of AlPO4-5 (AFI) crystals are measured in the temperature range from 80 to 298 K. The excitonic energy of the isolated Se chains is observed to shift to lower ...
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
THE pleckstrin homology (PH) domain is a new protein module of around 100 amino acids found in several proteins involved in signal transduction1–5. Although its specific function has yet to be elucidated, the carboxy-terminal ...