Now showing items 81-90 of 672
Encapsulation of Au nanoparticles by poly(4-Vinylpyridine)-block-polystyrene-block-poly(4-Vinylpyridine) for controlled chain assembly
We report a facile method to encapsulate Au nanoparticles (NPs) in an amphiphilic ABA triblock copolymer, poly(4-vinylpyridine)-block-polystyrene-block-poly(4-vinylpyridine) (P4VP-b-PS-b-P4VP), forming Au@P4VP-b-PS-b-P4VP ...
Cobalt-catalyzed enantioselective directed C-H alkylation of indole with styrenes
A cobalt–chiral phosphoramidite catalyst promotes enantioselective imine-directed C2-alkylation of Boc-protected indoles with styrenes. The reaction affords 1,1-diarylethane products in moderate to good yields with good ...
Diastereoselective aminooxygenation and diamination of alkenes with amidines by hypervalent iodine(III) reagents
Diastereoselective anti-aminooxygenation and anti-diamination of alkenes with amidines were enabled by hypervalent iodine(III) reagents such as PhI(OCOR)2 and PhI(NMs2)2, respectively. The present transformation offers ...
Building a lewis acidic phosphorus
Using the σ- and п-donating properties of carbodiphosphorane ligands, we recently synthesized a phosphorus (III)-containing dication. It is observed to undergo interesting reactivity with PMe3, H2O and MeOH.
Protein arginine methyltransferase 6 enhances ligand-dependent and -independent activity of estrogen receptor α via distinct mechanisms
Recent studies reported that protein arginine methyltransferase 6 (PRMT6) enhances estrogen-induced activity of estrogen receptor α (ERα) and dysfunction of PRMT6 is associated with overall better survival for ERα-positive ...
Fabrication and characterization of germanium-on-insulator through epitaxy, bonding, and layer transfer
A scalable method to fabricate germanium on insulator (GOI) substrate through epitaxy, bonding, and layer transfer is reported. The germanium (Ge) epitaxial film is grown directly on a silicon (Si) (001) donor wafer using ...
Crystallization and preliminary crystallographic analysis of human aquaporin 1 at a resolution of 3.28 Å
Aquaporin water channels (AQPs) are found in almost every organism from humans to bacteria. In humans, 13 classes of AQPs control water and glycerol homeostasis. Knockout studies have suggested that modulating the activity ...
A force balance model for the motion, impact, and bounce of bubbles
A force balance model has been developed to predict the terminal velocity of a sub-millimetric bubble as its rises in water under buoyancy. The dynamics of repeated collisions and rebounds of the bubble against a horizontal ...
N-heterocyclic carbene organocatalytic reductive β,β-coupling reactions of nitroalkenes via radical intermediates
An unprecedented N-heterocyclic carbene catalytic reductive β,β-carbon coupling of α,β-nitroalkenes, by using an organic substrate to mimic the one-electron oxidation role of the pyruvate ferredoxin oxidoreductase (PFOR) ...
Identification and characterization of an eIF4e DNA aptamer that inhibits proliferation with high throughput sequencing
Development of DNA aptamer screens that are both simple and informative can increase the success rate of DNA aptamer selection and induce greater adoption. High eIF4e levels contribute to malignancies, thus eIF4e presents ...