Now showing items 1-20 of 18113

    • “Regardless of Religion” : Building a Stronger Singaporean Society 

      Jayakumar, Shashi; Nur Diyanah Anwar (2018-02-12)
      A little-noticed but significant 2017 survey on the Singaporean public’s responses to scenarios following hypothetical terror attacks appears to suggest this: notwithstanding the progress made after 52 years in our ...
    • Discrete-time day-to-day dynamic congestion pricing scheme considering multiple equilibria 

      Han, Linghui; Wang, David Zhi Wei; Lo, Hong K.; Zhu, Chengjuan; Cai, Xingju (2017)
      In this study, we focus on the discrete-time day-to-day dynamic congestion pricing scheme which varies the toll on a day-to-day basis and aims to drive the traffic system to a given objective traffic equilibrium state. As ...
    • HCl, KCl and KOH solvation resolved solute-solvent interactions and solution surface stress 

      Zhang, Xi; Xu, Yan; Zhou, Yong; Gong, Yinyan; Huang, Yongli; Sun, Chang Qing (2017)
      An incorporation of the hydrogen bond (O:HO or HB) cooperativity notion, contact angle detection, and the differential phonon spectrometrics (DPS) has enabled us to gain refined information on the HCl, KCl and KOH solvation ...
    • Flow characteristics around a circular cylinder undergoing vortex-induced vibration in the initial branch 

      Hsieh, Shih-Chun; Low, Ying Min; Chiew, Yee-Meng (2016)
      Vortex-induced vibration (VIV) has been studied extensively and much attention has been devoted to the “lock-in” phenomenon, which is primarily responsible for fatigue damage to structures. Nevertheless, the behavior of ...
    • Resolving H(Cl, Br, I) capabilities of transforming solution hydrogen-bond and surface-stress 

      Zhang, Xi; Zhou, Yong; Gong, Yinyan; Huang, Yongli; Sun, Changqing (2017)
      A combination of differential phonon spectrometrics (DPS) and DFT calculations verified the essentiality of H+ ↔ H+ point fragilization and X− polarization dictating the surface stress of HX (X = Cl, Br, I) solutions. H+ ...
    • Pyeongchang Winter Olympics – What’s Behind the Korean Unification Flag? 

      Ho, Shawn (2018-02-08)
      The Korean unification flag, in its first version, consists of a blue and undivided Korean peninsula as well as Jeju island to its south. There is a lot more to this flag than meets the eye.
    • ASEAN Digital Economy: A New Pillar? 

      Vineles, Phidel (2018-02-09)
      As ASEAN chairman this year, Singapore is focusing on the digital economy. How can the digital economy become a key driver to achieve a highly integrated and dynamic ASEAN Economic Community (AEC)?
    • Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality 

      Kitagawa, Mayumi; Liao, Pei-Ju; Lee, Kyung Hee; Wong, Jasmine; Shang, See Cheng; Minami, Noriaki; Sampetrean, Oltea; Saya, Hideyuki; Dai, Lingyun; Prabhu, Nayana; Diam, Go Ka; Sobota, Radoslaw; Larsson, Andreas; Nordlund, Pär; McCormick, Frank; Ghosh, Sujoy; Epstein, David M.; Dymock, Brian W.; Lee, Sang Hyun (2017)
      Achieving robust cancer-specific lethality is the ultimate clinical goal. Here, we identify a compound with dual-inhibitory properties, named a131, that selectively kills cancer cells, while protecting normal cells. Through ...
    • Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices 

      Wang, Mengmeng; Ong, Sharon Lee-Ling; Dauwels, Justin; Asada, H. Harry (2017)
      Angiogenesis, the growth of new blood vessels from pre-existing vessels, is a critical step in cancer invasion. Better understanding of the angiogenic mechanisms is required to develop effective antiangiogenic therapies ...
    • A robot-aided visuo-motor training that improves proprioception and spatial accuracy of untrained movement 

      Elangovan, Naveen; Cappello, Leonardo; Masia, Lorenzo; Aman, Joshua; Konczak, Jürgen (2017)
      Proprioceptive function can become enhanced during motor learning. Yet, we have incomplete knowledge to what extent proprioceptive function is trainable and how a training that enhances proprioception may infuence performance ...
    • Characterization of liposomal carriers for the trans-scleral transport of Ranibizumab 

      Joseph, Rini Rachel; Tan, Dulcia Wei Ni; Ramon, Moreno Raja Miguel; Natarajan, Jayaganesh V.; Agrawal, Rupesh; Wong, Tina TzeeLing; Venkatraman, Subramanian (2017)
      Age-related macular degeneration (AMD) is a leading cause of blindness in the modern world. The standard treatment regimen for neovascular AMD is the monthly/bimonthly intravitreal injection of anti-VEGF agents such as ...
    • Self-adaptive Bioinspired Hummingbird-wing Stimulated Triboelectric Nanogenerators 

      Ahmed, Abdelsalam; Hassan, Islam; Song, Peiyi; Gamaleldin, Mohamed; Radhi, Ali; Panwar, Nishtha; Tjin, Swee Chuan; Desoky, Ahmed Y.; Sinton, David; Yong, Ken-Tye; Zu, Jean (2017)
      Bio-inspired technologies have remarkable potential for energy harvesting from clean and sustainable energy sources. Inspired by the hummingbird-wing structure, we propose a shape-adaptive, lightweight triboelectric ...
    • Estrogen reprograms the activity of neutrophils to foster protumoral microenvironment during mammary involution 

      Chung, Hwa Hwa; Or, Yu Zuan; Shrestha, Smeeta; Loh, Jia Tong; Lim, Chew Leng; Ong, Zoe; Woo, Amanda Rui En; Su, I-Hsin; Lin, Valerie Chun Ling (2017)
      Epidemiological studies have indicated increased risk for breast cancer within 10 years of childbirth. Acute inflammation during mammary involution has been suggested to promote this parity-associated breast cancer. We ...
    • Exceptional increase in the creep life of magnesium rare-earth alloys due to localized bond stiffening 

      Choudhuri, Deep; Srinivasan, Srivilliputhur G.; Gibson, Mark A.; Zheng, Yufeng; Jaeger, David L.; Fraser, Hamish L.; Banerjee, Rajarshi (2017)
      Several recent papers report spectacular, and unexpected, order of magnitude improvement in creep life of alloys upon adding small amounts of elements like zinc. This microalloying effect raises fundamental questions ...
    • Alternative extrapolation-based symmetry boundary implementations for the axisymmetric lattice Boltzmann method 

      Zhang, Liangqi; Yang, Shiliang; Zeng, Zhong; Chen, Jie; Wang, Lingquan; Chew, Jia Wei (2017)
      In this study, alternative symmetry boundary implementations for the axisymmetric lattice Boltzmann (LB) method are proposed based on the nonequilibrium extrapolation and the direct extrapolation schemes. The proposed ...
    • Predicting Crash Rate Using Logistic Quantile Regression With Bounded Outcomes 

      Xu, Xuecai; Duan, Li (2017)
      Various approaches and perspectives have been presented in safety analysis during the last decade, but when some continuous outcome variables take on values within a bounded interval, the conventional statistical methods ...
    • Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner 

      Thion, Morgane Sonia; Low, Donovan; Silvin, Aymeric; Chen, Jinmiao; Grisel, Pauline; Schulte-Schrepping, Jonas; Blecher, Ronnie; Ulas, Thomas; Squarzoni, Paola; Hoeffel, Guillaume; Coulpier, Fanny; Siopi, Eleni; David, Friederike Sophie; Scholz, Claus; Foo, Shihui; Lum, Josephine; Amoyo, Arlaine Anne; Larbi, Anis; Poidinger, Michael; Buttgereit, Anne; Lledo, Pierre-Marie; Greter, Melanie; Chan, Jerry Kok Yen; Amit, Ido; Beyer, Marc; Schultze, Joachim Ludwig; Schlitzer, Andreas; Pettersson, Sven; Ginhoux, Florent; Garel, Sonia (2017)
      Microglia are embryonically seeded macrophages that contribute to brain development, homeostasis, and pathologies. It is thus essential to decipher how microglial properties are temporally regulated by intrinsic and extrinsic ...
    • Our Gut Microbiome: The Evolving Inner Self 

      Kundu, Parag; Blacher, Eran; Elinav, Eran; Pettersson, Sven (2017)
      The “holobiont” concept, defined as the collective contribution of the eukaryotic and prokaryotic counterparts to the multicellular organism, introduces a complex definition of individuality enabling a new comprehensive ...
    • Inter-Species Host Gene Expression Differences in Response to Human and Avian Influenza A Virus Strains 

      Taye, Biruhalem; Yeo, Dawn; Lee, Raphael Tze Chuen; Tan, Boon Huan; Sugrue, Richard J.; Maurer-Stroh, Sebastian (2017)
      Low pathogenic avian influenza (LPAI) viruses are a source of sporadic human infections and could also contribute to future pandemic outbreaks but little is known about inter-species differences in the host responses to ...
    • Theranostic Probes for Targeting Tumor Microenvironment: An Overview 

      Sikkandhar, Musafar Gani; Nedumaran, Anu Maashaa; Ravichandar, Roopa; Singh, Satnam; Santhakumar, Induja; Goh, Zheng Cong; Mishra, Sachin; Archunan, Govindaraju; Gulyás, Balázs; Padmanabhan, Parasuraman (2017)
      Long gone is the time when tumors were thought to be insular masses of cells, residing independently at specific sites in an organ. Now, researchers gradually realize that tumors interact with the extracellular matrix ...