|
| | | Issue Date | Title | Author(s) |
| 1 | | 2022 | Discrepant serological findings in SARS-CoV-2 PCR-negative hospitalized patients with fever and acute respiratory symptoms during the pandemic | Cross, Gail B.; Naftalin, Claire M.; Ngiam, Jinghao N.; Bagdasarian, Natasha; Poh, Chek M.; Goh, Yun S.; Chia, Wan N.; Amrun, Siti N.; Tham, Sai M.; Teng, Hazel; Alagha, Rawan; Kumar, Shoban K.; Tan, Shaun S. Y.; Wang, Lin F.; Tambyah, Paul A.; Renia, Laurent; Fisher, Dale; Ng, Lisa F. P. |
| 2 |  | 2022 | Mechanisms underlying C-type inactivation in Kv channels: lessons from structures of human Kv1.3 and fly shaker-IR channels | Ong, Seow Theng; Tyagi, Anu; Chandy, Kanianthara George; Bhushan, Shashi |
| 3 |  | 2023 | Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters | Rouers, Angeline; Wong, Nathan; Goh, Yun Shan; Torres-Ruesta, Anthony; Tay, Matthew Zirui; Chang, Zi Wei; Fong, Siew-Wai; Neo, Vanessa; Kam, Isaac Kai Jie; Yeo, Nicholas Kim-Wah; Huang, Yuling; Loh, Chiew Yee; Hor, Pei Xiang; Wong, Joel Xu En; Tan, Yong Jie; Macary, Paul A.; Qian, Xinlei; Bei, Wang; Ngoh, Eve Zi Xian; Salleh, Siti Nazihah Mohd; Wang, Cheng-I; Poh, Xuan Ying; Rao, Suma; Chia, Po Ying; Ong, Sean W. X.; Lee, Tau Hong; Lin, Ray J. H.; Lim, Clarissa; Teo, Jefanie; Ren, Ee Chee; Lye, David C.; Young, Barnaby Edward; Ng, Lisa F. P.; Renia, Laurent |
| 4 | | 2021 | The steroidal lactone withaferin A impedes T-cell motility by inhibiting the kinase ZAP70 and subsequent kinome signaling | Mobashar Hussain Urf Turabe Fazil; Chirumamilla, Chandra Sekhar; Perez-Novo, Claudina; Wong, Brandon Han Siang; Kumar, Sunil; Sze, Siu Kwan; Berghe, Wim Vanden; Verma, Navin Kumar |
| 5 | | 2022 | Shotgun metagenomic sequencing analysis of ocular surface microbiome in Singapore residents with mild dry eye | Tong, Louis; Constancias, Florentin; Hou, Aihua; Chua, Song Lin; Drautz-Moses, Daniela Isabel; Schuster, Stephan Christoph; Yang, Liang; Williams, Rohan B. H.; Kjelleberg, Staffan |
| 6 | | 2022 | Intranasal delivery of RIG-I agonist drives pulmonary myeloid cell activation in mice | Nair, Sajith; Wu, Yilun; Nguyen, Trinh Mai; Fink, Katja; Luo, Dahai; Ruedl, Christiane |
| 7 | | 2022 | Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L) | Leow, Melvin Khee-Shing; Rengaraj, Anantharaj; Narasimhan, Kothandaraman; Verma, Sanjay K.; Yaligar, Jadegoud; Thu, Giang Le Thi; Sun, Lijuan; Goh, Hui Jen; Govindharajulu, Priya; Sadananthan, Suresh Anand; Michael, Navin; Meng, Wei; Gallart-Palau, Xavier; Sun, Lei; Karnani, Neerja; Sze, Siu Kwan; Velan, S. Sendhil |
| 8 | | 2022 | Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold | Cheong, Ezekiel Ze Ken; Quek, Jun-Ping; Xin, Liu; Li, Chaoqiang; Chan, Jing Yi; Liew, Chong Wai; Mu, Yuguang; Zheng, Jie; Luo, Dahai |
| 9 | | 2015 | The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development | Luo, Dahai; Vasudevan, Subhash; Lescar, Julien |
| 10 | | 2017 | Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner | Thion, Morgane Sonia; Low, Donovan; Silvin, Aymeric; Chen, Jinmiao; Grisel, Pauline; Schulte-Schrepping, Jonas; Blecher, Ronnie; Ulas, Thomas; Squarzoni, Paola; Hoeffel, Guillaume; Coulpier, Fanny; Siopi, Eleni; David, Friederike Sophie; Scholz, Claus; Foo, Shihui; Lum, Josephine; Amoyo, Arlaine Anne; Larbi, Anis; Poidinger, Michael; Buttgereit, Anne; Lledo, Pierre-Marie; Greter, Melanie; Chan, Jerry Kok Yen; Amit, Ido; Beyer, Marc; Schultze, Joachim Ludwig; Schlitzer, Andreas; Pettersson, Sven; Ginhoux, Florent; Garel, Sonia |
| 11 | | 2016 | Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma | McGeachie, Michael J.; Yates, Katherine P.; Zhou, Xiaobo; Guo, Feng; Sternberg, Alice L.; Van Natta, Mark L.; Wise, Robert A.; Szefler, Stanley J.; Sharma, Sunita; Kho, Alvin T.; Cho, Michael H.; Croteau-Chonka, Damien C.; Castaldi, Peter J.; Jain, Gaurav; Sanyal, Amartya; Zhan, Ye; Lajoie, Bryan R.; Dekker, Job; Stamatoyannopoulos, John; Covar, Ronina A.; Zeiger, Robert S.; Adkinson, N. Franklin; Williams, Paul V.; Kelly, H. William; Grasemann, Hartmut; Vonk, Judith M.; Koppelman, Gerard H.; Postma, Dirkje S.; Raby, Benjamin A.; Houston, Isaac; Lu, Quan; Fuhlbrigge, Anne L.; Tantisira, Kelan G.; Silverman, Edwin K.; Tonascia, James; Weiss, Scott T.; Strunk, Robert C. |
| 12 | | 2016 | Structure of the NS2B-NS3 protease from Zika virus after self-cleavage | Phoo, Wint Wint; Li, Yan; Zhang, Zhenzhen; Lee, Michelle Yueqi; Loh, Ying Ru; Tan, Yaw Bia; Ng, Elizabeth Yihui; Lescar, Julien; Kang, CongBao; Luo, Dahai |
| 13 | | 2018 | The molecular functions of hepatocyte nuclear factors - in and beyond the liver | Lau, Hwee Hui; Ng, Natasha Hui Jin; Loo, Larry Sai Weng; Joanita Jasmen; Teo, Adrian Kee Keong |
| 14 | | 2019 | Reactive oxygen species : a volatile driver of field cancerization and metastasis | Liao, Zehuan; Chua, Damien; Tan, Nguan Soon |
| 15 | | 2014 | The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication | Tay, Moon Y. F.; Saw, Wuan Geok; Zhao, Yongqian; Chan, Kitti W. K.; Singh, Daljit; Chong, Yuwen; Forwood, Jade K.; Ooi, Eng Eong; Grüber, Gerhard; Lescar, Julien; Luo, Dahai; Vasudevan, Subhash G. |
| 16 | | 2015 | Establishing Criteria for Human Mesenchymal Stem Cell Potency | Samsonraj, Rebekah M.; Rai, Bina; Sathiyanathan, Padmapriya; Puan, Kia Joo; Rötzschke, Olaf; Hui, James H.; Raghunath, Michael; Stanton, Lawrence Walter; Nurcombe, Victor; Cool, Simon M. |
| 17 | | 2017 | Exploiting the synthetic lethality between terminal respiratory oxidases to kill
Mycobacterium tuberculosis
and clear host infection | Hasenoehrl, Erik J.; Koh, Vanessa H.; Ang, Michelle L. T.; Sajorda, Dannah R.; Hards, Kiel; Grüber, Gerhard; Alonso, Sylvie; Cook, Gregory M.; Berney, Michael; Pethe, Kevin; Kalia, Nitin Pal; Ab Rahman, Nurlilah Binte |
| 18 | | 2019 | Exploration and development of PPAR modulators in health and disease : an update of clinical evidence | Cheng, Hong Sheng; Tan, Wei Ren; Low, Zun Siong; Marvalim, Charlie; Lee, Justin Yin Hao; Tan, Nguan Soon |
| 19 | | 2015 | High-Performance Capacitive Deionization Disinfection of Water with Graphene Oxide-graft-Quaternized Chitosan Nanohybrid Electrode Coating | Wang, Yilei; El-Deen, Ahmed G.; Li, Peng; Oh, Bernice Hui Lin; Guo, Zanru; Khin, Mya Mya; Vikhe, Yogesh Shankar; Wang, Jing; Hu, Rebecca G.; Boom, Remko M.; Kline, Kimberly A.; Becker, David Lawrence; Duan, Hongwei; Chan-Park, Mary B. |
| 20 | | 2016 | Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels | Drautz-Moses, Daniela Isabel; Schuster, Stephan Christoph; Kjelleberg, Staffan; Givskov, Michael; Yang, Liang; Chua, Song Lin; Ding, Yichen; Liu, Yang; Cai, Zhao; Zhou, Jianuan; Swarup, Sanjay |
| 21 | | 2016 | Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ | Tan, Nguan Soon; Vázquez-Carrera, Manuel; Montagner, Alexandra; Sng, Ming Keat; Guillou, Hervé; Wahli, Walter |
| 22 | | 2019 | Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment | Cheng, Hong Sheng; Lee, Jeannie Xue Ting; Wahli, Walter; Tan, Nguan Soon |
| 23 | | 2016 | Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity | Chng, Song Hui; Kundu, Parag; Dominguez-Brauer, Carmen; Teo, Wei Ling; Mak, Tak Wah; Pettersson, Sven; Kawajiri, Kaname; Fujii-Kuriyama, Yoshiaki |
| 24 | | 2014 | Endoplasmic reticulum stress response in yeast and humans | Wu, Haoxi; Ng, Benjamin S. H.; Thibault, Guillaume |
| 25 | | 2019 | Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease | Park, Jung Eun; Sze, Siu Kwan; Adav, Sunil Shankar |
| 26 | | 2021 | Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis | Lee, Bei Shi; Hards, Kiel; Engelhart, Curtis A.; Hasenoehrl, Erik J.; Kalia, Nitin Pal; Mackenzie, Jared S.; Sviriaeva, Ekaterina; Chong, Sherilyn Shi Min; Manimekalai, Malathy Sony S.; Koh, Vanessa H.; Chan, John; Xu, Jiayong; Alonso, Sylvie; Miller, Marvin J.; Steyn, Adrie J. C.; Grüber, Gerhard; Schnappinger, Dirk; Berney, Michael; Cook, Gregory M.; Moraski, Garrett C.; Pethe, Kevin |
| 27 | | 2021 | Sex-specific accelerated decay in time/activity-dependent plasticity and associative memory in an animal model of Alzheimer's disease | Navakkode, Sheeja; Gaunt, Jessica Ruth; Pavon, Maria Vazquez; Bansal, Vibhavari Aysha; Abraham, Riya Prasad; Chong, Yee Song; Ch'ng, Toh Hean; Sajikumar, Sreedharan |
| 28 | | 2022 | Feruloyl sucrose esters: potent and selective inhibitors of α-glucosidase and α-amylase | Devaraj, Surabhi; Yip, Yew Mun; Panda, Parthasarathi; Ong, Li Lin; Wong, Kathy Pooi Wen; Zhang, Dawei; Ali, Yusuf; Judeh, Zaher |
| 29 | | 2022 | Effects of ozone-vegetation interactions on meteorology and air quality in China using a two-way coupled land-atmosphere model | Zhu, Jiachen; Tai, Amos P. K.; Yim, Steve Hung Lam |
| 30 | | 2022 | N-WASP attenuates cell proliferation and migration through ERK2-dependent enhanced expression of TXNIP | Chung, Yat Joong; Salvi, Amrita; Kalailingam, Pazhanichamy; Alnawaz, Myra; Tan, Suat Hoon; Pan, Jiun Yit; Tan, Nguan Soon; Thanabalu, Thirumaran |
| 31 | | 2021 | DNA-derived nanostructures selectively capture gram-positive bacteria | Kim, Chan-Jin; Si, Zhangyong; Reghu, Sheethal; Guo, Zhong; Zhang, Kaixi; Li, Jianghua; Chan-Park, Mary B. |
| 32 | | 2022 | An investigation of how normalisation and local modelling techniques confound machine learning performance in a mental health study | Zhang, Xinxin; Lee, Jimmy; Goh, Wilson Wen Bin |
| 33 | | 2018 | Dachshund depletion disrupts mammary gland development and diverts the composition of the mammary gland progenitor pool | Jiao, Xuanmao; Li, Zhiping; Wang, Min; Katiyar, Sanjay; Di Sante, Gabriele; Farshchian, Mehdi; Wu, Kongming; Tabas, Ira; Spike, Benjamin T.; South, Andrew P.; Cocola, Cinzia; Colombo, Daniele; Reinbold, Rolland; Zucchi, Ileana; Pestell, Richard George |
| 34 | | 2020 | Navigating conflicts of justice in the use of race and ethnicity in precision medicine | Schaefer, G. Owen; Tai, E. Shyong; Sun, Shirley Hsiao-Li |
| 35 | | 2021 | Cell membrane-coated electrospun fibers enhance keratinocyte growth through cell-type specific interactions | Chooi, Wai Hon; Dong, Quanbin; Low, Jeremy Zhi Yan; Yuen, Clement; Chin, Jiah Shin; Lin, Junquan; Ong, William; Liu, Quan; Chew, Sing Yian |
| 36 | | 2022 | A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication | Wang, Sai; Chan, Kitti Wing Ki; Tan, Min Jie Alvin; Flory, Charlotte; Luo, Dahai; Lescar, Julian; Forwood, Jade K.; Vasudevan, Subhash G. |
| 37 | | 2019 | Ethnicity-specific skeletal muscle transcriptional signatures and their relevance to insulin resistance in Singapore | Tan, Amelia Li Min; Langley, Sarah R.; Tan, Chee Fan; Chai, Jin Fang; Khoo, Chin Meng; Leow, Melvin Khee-Shing; Khoo, Eric Yin Hao; Moreno-Moral, Aida; Pravenec, Michal; Rotival, Maxime; Sadananthan, Suresh Anand; Velan, S. Sendhil; Venkataraman, Kavita; Chong, Yap Seng; Lee, Yung Seng; Sim, Xueling; Stunkel, Walter; Liu, Mei Hui; Tai, E. Shyong; Petretto, Enrico |
| 38 | | 2021 | Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents | Zhang, Kaixi; Raju, Cheerlavancha; Zhong, Wenbin; Pethe, Kevin; Gründling, Angelika; Chan-Park, Mary B. |
| 39 | | 2022 | Destabilization of β cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes | Zheng, Xiaofeng; Ho, Calvin Qing Wei; Chua, Minni; Stelmashenko, Olga; Yeo, Xin Yi; Muralidharan, Sneha; Torta, Federico; Chew, Elaine Guo Yan; Lian, Michelle Mulan; Foo, Jia Nee; Jung, Sangyong; Wong, Sunny Hei; Tan, Nguan Soon; Tong, Nanwei; Rutter, Guy A.; Wenk, Markus R.; Silver, David L.; Berggren, Per-Olof; Ali, Yusuf |
| 40 | | 2019 | Structure-guided design of immunomodulatory RNAs specifically targeting the cytoplasmic viral RNA sensor RIG-I | Yong, Hui Yee; Zheng, Jie; Ho, Victor Chin Yong; Nguyen, Mai Trinh; Fink, Katja; Griffin, Patrick R.; Luo, Dahai |
| 41 | | 2020 | Exploring extracellular vesicles biogenesis in hypothalamic cells through a heavy isotope pulse/trace proteomic approach | Tan, Chee Fan; Teo, Hui San; Park, Jung Eun; Dutta, Bamaprasad; Tse, Shun Wilford; Leow, Melvin Khee-Shing; Wahli, Walter; Sze, Siu Kwan |
| 42 | | 2022 | Are batch effects still relevant in the age of big data? | Goh, Wilson Wen Bin ; Yong, Chern Han; Wong, Limsoon |
| 43 | | 2019 | Pyruvate kinase regulates the pentose-phosphate pathway in response to hypoxia in mycobacterium tuberculosis | Zhong, Wenhe; Guo, Jingjing; Cui, Liang; Chionh, Yok Hian; Li, Kuohan; El Sahili, Abbas; Cai, Qixu; Yuan, Meng; Michels, Paul A. M.; Fothergill-Gilmore, Linda A.; Walkinshaw, Malcolm D.; Mu, Yuguang; Lescar, Julien; Dedon, Peter C. |
| 44 | | 2022 | Telacebec : an investigational antibacterial for the treatment of tuberculosis (TB) | Lee, Bei Shi; Pethe, Kevin |
| 45 | | 2021 | The habenula clock influences response to a stressor | Basnakova, Adriana; Cheng, Ruey-Kuang; Chia, Joanne Shu Ming; D'Agostino, Giuseppe; Suryadi; Tan, Germaine Jia Hui; Langley, Sarah Raye; Jesuthasan, Suresh |
| 46 | | 2019 | Depletion of gram-positive bacteria impacts hepatic biological functions during the light phase | Oh, Penny Hui Yun; Ellero-Simatos, Sandrine; Manickam, Ravikumar; Tan, Nguan Soon; Guillou, Hervé; Wahli, Walter |
| 47 | | 2022 | Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia | Zhang, Qian; Matuozzo, Daniela; Le Pen, Jérémie; Lee, Danyel; Moens, Leen; Asano, Takaki; Bohlen, Jonathan; Liu, Zhiyong; Moncada-Velez, Marcela; Kendir-Demirkol, Yasemin; Jing, Huie; Bizien, Lucy; Marchal, Astrid; Abolhassani, Hassan; Delafontaine, Selket; Bucciol, Giorgia; Bayhan, Gulsum Ical; Keles, Sevgi; Kiykim, Ayca; Hancerli, Selda; Haerynck, Filomeen; Florkin, Benoit; Hatipoglu, Nevin; Ozcelik, Tayfun; Morelle, Guillaume; Zatz, Mayana; Ng, Lisa F. P.; Lye, David C.; Young, Barnaby Edward; Leo, Yee Sin; Dalgard, Clifton L.; Lifton, Richard P.; Renia, Laurent; Meyts, Isabelle; Jouanguy, Emmanuelle; Hammarström, Lennart; Pan-Hammarström, Qiang; Boisson, Bertrand; Bastard, Paul; Su, Helen C.; Boisson-Dupuis, Stéphanie; Abel, Laurent; Rice, Charles M.; Zhang, Shen-Ying; Cobat, Aurélie; Casanova, Jean-Laurent |
| 48 | | 2017 | Inter-Species Host Gene Expression Differences in Response to Human and Avian Influenza A Virus Strains | Taye, Biruhalem; Yeo, Dawn; Lee, Raphael Tze Chuen; Tan, Boon Huan; Sugrue, Richard J.; Maurer-Stroh, Sebastian |
| 49 | | 2017 | Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile | Ku, Chee Wai; Tan, Zhen Wei; Lim, Mark Kit; Tam, Zhi Yang; Lin, Chih-Hsien; Ng, Sean Pin; Allen, John Carson; Lek, Sze Min; Tan, Thiam Chye; Tan, Nguan Soon |
| 50 | | 2021 | Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore | Wang, Bei; Goh, Yun Shan; Prince, Tessa; Ngoh, Eve Zi Xian; Salleh, Siti Nazihah Mohd; Hor, Pei Xiang; Loh, Chiew Yee; Fong, Siew Wai; Hartley, Catherine; Tan, Seow-Yen; Young, Barnaby Edward; Leo, Yee Sin; Lye, David Chien Boon; Maurer-Stroh, Sebastian; Ng, Lisa F. P.; Hiscox, Julian A.; Renia, Laurent; Wang, Cheng-I |
